Synthesis and Antimicrobial Evaluation of Some New Pyrazolo[1,5-a]pyrimidine and Pyrazolo[1,5-c]triazine Derivatives Containing Sulfathiazole Moiety

Autor:	Elsherbiny Hamdy El-Sayed, Ahmed Ali Fadda, Ahmed Mohamed El-Saadaney
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	sulfathiazole benzenesulfonamide pyrazole antimicrobial evaluation Chemistry QD1-999
Zdroj:	Acta Chimica Slovenica, Vol 67, Iss 4, Pp 1024-1034 (2020)
Druh dokumentu:	article
ISSN:	1318-0207 1580-3155
DOI:	10.17344/acsi.2019.5007
Popis:	A number of important fused heterocyclic systems have been prepared by the reaction of 4-((3,5-diamino-1H-pyrazol-4-yl)-diazenyl)-N-(thiazol-2-yl)-benzenesulfonamide with some bifunctional nucleophiles such as ethyl acetoacetate, acetylacetone or arylidenemalonononitrile derivatives to obtain pyrazolo[1,5-a]pyrimidine derivatives. The structures of the newly synthesized compounds were determined based on their IR, 1H and 13C NMR and mass spectroscopic data. Most of the compounds produced showed good antibacterial and antifungal activity.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/5458116d94db40d79b2a3c2460c864fa Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF