Human gelatin thrombin matrix with rifampin for the treatment of prosthetic vascular graft infections

Autor: José L. Ortiz-Fullana, MD, MPH, Cristina Sánchez, MDc, Pedro Pagán, MDc, Patricia Mulero-Soto, MD, Gabriel Dieppa-Barnes, MD, Rafael Santini-Domínguez, MD, RPVI, FACS, Jorge L. Martinez-Trabal, MD, RPVI, FACS
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Vascular Surgery Cases and Innovative Techniques, Vol 10, Iss 1, Pp 101365- (2024)
Druh dokumentu: article
ISSN: 2468-4287
DOI: 10.1016/j.jvscit.2023.101365
Popis: We aim to describe and report on a novel graft preservation technique using a human gelatin thrombin matrix with rifampin for the treatment of vascular graft infections. Eight patients with vascular graft infections were included, one with bilateral infections, for a total of nine cases from January 2016 through June 2021. All the patients underwent wound exploration and placement of human gelatin thrombin matrix with rifampin. No deaths or allergic reactions had been reported at the 30-day follow-up, with only one major amputation. The graft and limb salvage rates were 77.8% at the 1-year follow-up. The mean time to a major amputation was 122 days, and the mean time to graft excision was 30 days.
Databáze: Directory of Open Access Journals