Initial experience with a novel resection and plication (RAP) method for acid reflux: a pilot study
| Autor: | Petros C. Benias, Lionel D’Souza, Gloria Lan, Craig Gluckman, Sumant Inamdar, Arvind J. Trindade, Larry S. Miller, David L. Carr-Locke |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Endoscopy International Open, Vol 06, Iss 04, Pp E443-E449 (2018) |
| Druh dokumentu: | article |
| ISSN: | 2364-3722 2196-9736 |
| DOI: | 10.1055/s-0044-101453 |
| Popis: | Background and study aims Current endoscopic therapies for gastroesophageal reflux disorder (GERD) are limited by technical complexity, and/or cost. We sought to evaluate the success of a novel resection and plication (RAP) anti-reflux procedure. Patients and methods RAP was performed on 10 patients with GERD refractory to proton pump inhibitor (PPI) therapy. RAP consists of semi-circumferential mucosectomy along with full-thickness plication of the lower esophageal sphincter (LES) and cardia. We assessed the technical success and safety as well as followed GERD-Health Related Quality of Life (GERD-HRQL) scores and medication usage. Results All patients underwent RAP without adverse events and were discharged on the same day. Only half of the patients required general anesthesia. Follow-up ranged from 5 to 24 months (median 9 months) and all patients had a significant improvement in their GERD-HRQL scores (P |
| Databáze: | Directory of Open Access Journals |
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