Synchronous bilateral Wilms’ tumor with liver metastasis

Autor: Senai Goitom Sereke, Abdirahman Omar Sahal, Vincent Mboizi, Felix Bongomin
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMC Urology, Vol 21, Iss 1, Pp 1-4 (2021)
Druh dokumentu: article
ISSN: 1471-2490
DOI: 10.1186/s12894-021-00859-8
Popis: Abstract Background Wilms’ tumor (nephroblastoma) is mostly unilateral; however, bilateral Wilms’ tumors are seen in about 5–8% of patients. This can be synchronous or metachronous. It is uncommon to get liver metastasis from bilateral Wilms’ tumor. Case presentation An 8-year-old male Ugandan presented with a history of abdominal swelling and flank pains for 1 year. There was no history of hematuria. Both ultrasound and computed tomography of the abdomen demonstrated multiple solid lesions in both kidneys and a huge solid mass in segments V, VI, VII and VIII of the liver. Histological examination of renal biopsy specimen was favorable for chemotherapeutic regimens. However, following a multidisciplinary tumor board consensus, a nephron-sparing surgery was deemed unsuitable, and he was managed conservatively with chemotherapy (adriamycin and vincristine) with a palliative intent. Conclusions Metastatic bilateral Wilms’ tumor has a particularly poor prognosis. There are no clear evidence-based guidelines for the management of this rare presentation. This patient benefited from early palliative care and symptom management.
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