| Autor: |
Ada Gjyrezi, Giuseppe Galletti, Jiaren Zhang, Daniel Worroll, Michael Sigouros, Seaho Kim, Victoria Cooley, Karla V. Ballman, Allyson J. Ocean, Manish A. Shah, Joseph M. Scandura, Andrea Sboner, David M. Nanus, Himisha Beltran, Scott Tagawa, Paraskevi Giannakakou |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2399-3642 |
| DOI: |
10.1038/s42003-021-02321-9 |
| Popis: |
Ada Gjyrezi et al. show that ddPCR can be used to accurately measure androgen receptor variant (AR-V) expression levels in single circulating tumor cells (CTCs) from prostate cancer patients. They show that current methods for isolating CTCs tend to underestimate the prevalence of AR-V and that a specific variant, AR-v567es, could be potentially used as a biomarker for an aggressive subtype of prostate cancer. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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