ASSOCIATION OF HELICOBACTER PYLORI INFECTION AND GASTROINTESTINAL DISEASE IN CHILDREN

Autor: Vanya Nedkova-Milanova, Zornitsa Gorcheva, Ivaylo Pakov, Milena D. Karcheva
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of IMAB, Vol 30, Iss 4, Pp 5819-5823 (2024)
Druh dokumentu: article
ISSN: 1312-773X
DOI: 10.5272/jimab.2024304.5819
Popis: Purpose: The purpose of this study was to assess the association between some clinical and epidemiological factors and the prevalence of Helicobacter Pylori (H. pylori) infection in children visited a paediatrics ambulatory care at University Hospital - Pleven for various symptoms pointing to gastritis and peptic ulcer. Materials and methods: an epidemiological study was conducted for the period June-September 2023. In total, 133 children aged from 2 to 18 years were evaluated. All visited a paediatrics ambulatory care at University Hospital - Pleven for various complaints pointing to gastritis and peptic ulcer. Results: During the study period, we recruited a total of 133 children and adolescents (age range 2-18 years, mean age 9.36 ± 4.08 years). More patients were males (54.14%) than females (45.86%). The most frequent symptoms were abdominal pain (51.88%), nausea and vomiting (21.80%), and losing weight (10.53%). The social status of the families is good - parents with a university education predominate (49.62%). There are risk factors for the presence of infection and the development of gastritis and ulcers in children: family history of H. pylori infection (47.37%) and use of unsuitable foods (48.87%). A high positivity is found for H. pylori (40.43%). Conclusions: Early diagnosis and etiological treatment of H. pylori infection reduces the risk of developing gastric complications like chronic gastritis, ulcer diseases and gastric cancer.
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