Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio

Autor: Alireza Abdshah, Mohammadreza Mirzaaghayan, Morteza Heidari, Sara Memarian, Mobina Amanollahi, Azadeh Nazeri, Behdad Gharib
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Health Science Reports, Vol 6, Iss 1, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 2398-8835
DOI: 10.1002/hsr2.1077
Popis: Abstract Background and Aims Due to increased rate of open‐heart surgeries in children, postsurgical mortality and morbidities have increasingly gained attention. Neurological complications are some of the most important postsurgical events. However, the number of studies regarding postsurgical neurological complications seems to be inadequate. We aimed to study the incidence of neurological complications following cardiac surgery in the pediatric cardiac intensive care unit (ICU) of the children's medical center. Methods This cross‐sectional study was conducted from March to September 2019. We included all of the children who underwent cardiac surgery and were admitted to ICU at CMC. We collected their demographic data, lab test results (white blood cell count, absolute neutrophile and lymphocyte counts) and calculated their Risk Adjustment for Congenital Heart Surgery (RACHS) score. We then documented neurological adverse events and investigated the associations between those events and the patients' data. Results Of the 267 studied patients, 14 developed neurological complications (5.2%); seven developed chorea (2.6%), four developed seizures (1.5%), and two developed both seizure and chorea (0.7%). One case developed subarachnoid hemorrhage (SAH). We observed that age (p = 0.000), weight (p = 0.000), and RACHS score (p = 0.006) were associated with the development of neurological complications. Additionally, we observed that “neutrophil to lymphocyte ratio” was not associated with the risk of postsurgical neurological complications. Conclusion Younger age, lower weight, and higher RACHS score were associated with neurological complications after operations. Given the importance of postsurgical neurological complications, further investigations should be carried out to cover this issue and discover preventive strategies for such morbidities.
Databáze: Directory of Open Access Journals
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