Prediabetes Phenotype Influences Improvements in Glucose Homeostasis with Resistance Training.

Autor: Joshua D Eikenberg, Jyoti Savla, Elaina L Marinik, Kevin P Davy, John Pownall, Mary E Baugh, Kyle D Flack, Soheir Boshra, Richard A Winett, Brenda M Davy
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: PLoS ONE, Vol 11, Iss 2, p e0148009 (2016)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0148009
Popis: To determine if prediabetes phenotype influences improvements in glucose homeostasis with resistance training (RT).Older, overweight individuals with prediabetes (n = 159; aged 60±5 yrs; BMI 33±4 kg/m2) completed a supervised RT program twice per week for 12 weeks. Body weight and composition, strength, fasting plasma glucose, 2-hr oral glucose tolerance, and Matsuda-Defronza estimated insulin sensitivity index (ISI) were assessed before and after the intervention. Participants were categorized according to their baseline prediabetes phenotype as impaired fasting glucose only (IFG) (n = 73), impaired glucose tolerance only (IGT) (n = 21), or combined IFG and IGT (IFG/IGT) (n = 65).Chest press and leg press strength increased 27% and 18%, respectively, following the 12-week RT program (both p0.05) following the intervention. However, 2-hr oral glucose tolerance improved in those with IGT (pre 8.94±0.72 mmol/l, post 7.83±1.11 mmol/l, p
Databáze: Directory of Open Access Journals