| Autor: |
Angela Maria Rocchigiani, Loris Bertoldi, Elisabetta Coradduzza, Giada Lostia, Davide Pintus, Rosario Scivoli, Maria Giovanna Cancedda, Mariangela Stefania Fiori, Roberto Bechere, Anna Pina Murtino, Giovanni Pala, Giusy Cardeti, Simona Macioccu, Maria Antonietta Dettori, Antonio Pintore, Ciriaco Ligios, Giantonella Puggioni |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Viruses, Vol 16, Iss 2, p 209 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1999-4915 |
| DOI: |
10.3390/v16020209 |
| Popis: |
Canine herpesvirus 1 (CaHV-1) infects dogs, causing neonatal death and ocular, neurological, respiratory, and reproductive problems in adults. Although CaHV-1 is widespread in canine populations, only four studies have focused on the CaHV-1 whole genome. In such context, two CaHV-1 strains from both the kidney and spleen of 20-day-old deceased French Bulldog puppies were recently isolated in Sardinia, Italy. The extracted viral DNA underwent whole-genome sequencing using the Illumina MiSeq platform. The Italian CaHV-1 genomes were nearly identical (>99%), shared the same tree branch, and clustered near the ELAL-1 (MW353125) and BTU-1 (KX828242) strains, enlarging the completely separated clade discussed by Lewin et al., in 2020. This study aims to provide new insights on the evolution of the CaHV-1, based on high-resolution whole-genome phylogenetic analysis, and on its clinicopathological characterization during a fatal outbreak in puppies. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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