PQBP5/NOL10 maintains and anchors the nucleolus under physiological and osmotic stress conditions

Autor: Xiaocen Jin, Hikari Tanaka, Meihua Jin, Kyota Fujita, Hidenori Homma, Maiko Inotsume, Huang Yong, Kenichi Umeda, Noriyuki Kodera, Toshio Ando, Hitoshi Okazawa
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-35602-w
Popis: The nucleolus is a liquid-liquid phase separation droplet that dynamically changes under stress. Here, the authors report PQBP5/NOL10 is a critical component of the nucleolus, maintaining its structure and position in the nucleus during osmotic stress.
Databáze: Directory of Open Access Journals