Understanding the impact of adult pertussis and current approaches to vaccination: A narrative review and expert panel recommendations
| Autor: | Peter Kardos, Jaime Correia de Sousa, Ulrich Heininger, Andreas Konstantopoulos, C. Raina MacIntyre, Donald Middleton, Terry Nolan, Alberto Papi, Adrian Rendon, Albert Rizzo, Kim Sampson, Alessandro Sette, Elizabeth Sobczyk, Tina Tan, Catherine Weil-Olivier, Birgit Weinberger, Tom Wilkinson, Carl Heinz Wirsing von König |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024) |
| Druh dokumentu: | article |
| ISSN: | 21645515 2164-554X 2164-5515 |
| DOI: | 10.1080/21645515.2024.2324547 |
| Popis: | ABSTRACTPertussis has several notable consequences, causing economic burden, increased strain on healthcare facilities, and reductions in quality of life. Recent years have seen a trend toward an increase in pertussis cases affecting older children and adults. To boost immunity, and protect vulnerable populations, an enduring approach to vaccination has been proposed, but gaps remain in the evidence surrounding adult vaccination that are needed to inform such a policy. Gaps include: the true incidence of pertussis and its complications in adults; regional variations in disease recognition and reporting; and incidence of severe disease, hospitalizations, and deaths in older adults. Better data on the efficacy/effectiveness of pertussis vaccination in adults, duration of protection, and factors leading to poor vaccine uptake are needed. Addressing the critical evidence gaps will help highlight important areas of unmet need and justify the importance of adult pertussis vaccination to healthcare professionals, policymakers, and payers. |
| Databáze: | Directory of Open Access Journals |
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