Uveitis and Rheumatological Diseases

Autor: Chloe Kwong Yee Cheung, Mandy Oi Man Wong, Carmen Kar Mun Chan, Ho Yin Chung
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Clinical Rheumatology and Immunology, Vol 21, Iss 2, Pp 70-77 (2021)
Druh dokumentu: article
ISSN: 2661-3417
2661-3425
26613417
DOI: 10.1142/S2661341721300068
Popis: Uveitis is the most common ophthalmological disorder in the field of rheumatology, accounting for a significant proportion of visual morbidity, both locally and internationally. Causative factors can be divided into infectious and noninfectious etiologies. The diagnosis of uveitis is a major challenge due to heterogeneity in presentation. The disease course may be acute monophasic, recurrent, or chronic relapsing. Complications include posterior synechiae, secondary cataract, ocular hypertension or glaucoma, macular edema, retinal vascular occlusion, epiretinal membrane, and so on, and ultimately visual loss. Antimicrobial therapy is indicated for infection, whereas noninfectious uveitis warrants a combination of steroids, immunosuppressives, and anti-inflammatory agents. With the advancement of biologics, treatment strategies in chronic, noninfectious uveitis have had multiple breakthroughs, particularly in treatment-resistant cases. This article provides a review of the diagnostic approach to uveitis based on symptomatology and ophthalmological findings, and discussion of relevant treatment modalities and strategies.
Databáze: Directory of Open Access Journals