MRI detection of mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE) on T1WI-CHESS

Autor: Elly Arizono, Zen-ichi Tanei, Keiya Iijima, Yukio Kimura, Yoko Shigemoto, Hiroyuki Maki, Midori Kusama, Kumiko Murayama, Masaki Iwasaki, Takashi Saito, Yuko Saito, Kazuhiro Saito, Noriko Sato
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Epilepsy & Behavior Reports, Vol 26, Iss , Pp 100674- (2024)
Druh dokumentu: article
ISSN: 2589-9864
DOI: 10.1016/j.ebr.2024.100674
Popis: Mild malformation of cortical development with oligodendroglial hyperplasia (MOGHE) is a recently proposed epileptogenic entity that is difficult to detect on MRI. We present a case of MOGHE that was successfully detected on T1WI-chemical shift-selective saturation (CHESS) MRI. The clinical presentation, MRI including T1WI-CHESS, functional images, and pathology findings of a 14-year-old Japanese girl diagnosed with MOGHE are described. T1WI-CHESS revealed an abnormal high signal along the affected lesion, whereas the findings shown by the other MR sequences were less obvious; interictal fluorodeoxyglucose-positron emission tomography indicated slightly decreased accumulation in the lesion, and subtraction ictal single photon emission computed tomography co-registered to MRI showed an increased blood flow. Together these observations suggest that T1WI-CHESS may be a useful MR sequence for detecting the lesions in patients with MOGHE.
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