A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA

Autor: Dong-Jie Tang, Xinyu Du, Qiang Shi, Jian-Ling Zhang, Yuan-Ping He, Yan-Miao Chen, Zhenhua Ming, Dan Wang, Wan-Ying Zhong, Yu-Wei Liang, Jin-Yang Liu, Jian-Ming Huang, Yun-Shi Zhong, Shi-Qi An, Hongzhou Gu, Ji-Liang Tang
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-16417-z
Popis: Riboswitches consist of an aptamer domain and expression platform, which senses a signal and regulates gene expression, respectively. Here the authors show that the expression platform of a SAM-I riboswitch from the Gram-negative bacteria can sense and bind uncharged an initiator Met tRNA to control the met operon.
Databáze: Directory of Open Access Journals