Long-Acting Luteinizing Hormone-Releasing Hormone Agonist for Ovarian Hyperstimulation Induced by Tamoxifen for Breast Cancer

Autor:	Nobue Kojima, Yui Yamasaki, Houu Koh, Masaru Miyashita, Hiroki Morita
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	Gynecology and obstetrics RG1-991
Zdroj:	Case Reports in Obstetrics and Gynecology, Vol 2018 (2018)
Druh dokumentu:	article
ISSN:	2090-6684 2090-6692
DOI:	10.1155/2018/4931852
Popis:	Tamoxifen treatment for breast cancer may induce ovarian cysts and supraphysiological levels of serum estrogen. We report successful management with luteinizing hormone-releasing hormone (LHRH) agonist of ovarian hyperstimulation induced by tamoxifen. A 49-year-old woman was operated on for invasive ductal carcinoma of the right breast. She received breast irradiation and adjuvant tamoxifen therapy. After 2 years, she had a cystic ovarian mass, and her serum concentration of estradiol was 1280 pg/mL. She was treated with an injection of 11.25 mg leuprolide acetate, a long-acting LHRH agonist, without abandoning tamoxifen therapy. The levels of estradiol decreased to
Databáze:	Directory of Open Access Journals
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