In vitro vasodilatory effect of aqueous leaf extract of Thymus serrulatus on thoracic aorta of Guinea pigs

Autor: Bekesho Geleta, Mebrahtu Eyasu, Selamu Kebamo, Asfaw Debella, Eyasu Makonnen, Abiy Abebe
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Asian Pacific Journal of Tropical Biomedicine, Vol 5, Iss 1, Pp 15-18 (2015)
Druh dokumentu: article
ISSN: 2221-1691
DOI: 10.1016/S2221-1691(15)30164-7
Popis: Objective: To investigate the vasodilatory effect of Thymus serrulatus (T. serrulatus) aqueous leaf extract on KCl (high K+, 80 mmol/L) induced precontracted isolated thoracic aorta rings on guinea pigs and the role of aorta endothelium on this action. Methods: Guinea pig thoracic aorta was removed and placed in an organ bath containing Krebs-Henseleit solution and aorta contractions were recorded isometrically. Results: The results revealed that T. serrulatus aqueous leaf extract (0.5-5 mg/mL) significantly (P
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