Case report: Successful use of ruxolitinib to treat interstitial pneumonia as an unusual primary presentation in primary myelofibrosis—two birds with one stone

Autor:	Pingping Xiao, Zhigao Dong, Qingqing Wang, Junnan Su, Yongquan Chen, Yiwan Lin
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	interstitial pneumonia Janus kinase 2 primary myelofibrosis ruxolitinib ten-eleven translocation 2 Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Frontiers in Oncology, Vol 14 (2024)
Druh dokumentu:	article
ISSN:	2234-943X
DOI:	10.3389/fonc.2024.1475036
Popis:	BackgroundInterstitial lung disease (ILD) is a rare clinical presentation of primary myelofibrosis (PMF).Case presentationWe report a case of ILD as the main manifestation on admission. A 58-year-old man was diagnosed with PMF owing to worsening anemia following treatment failure for conventional interstitial pneumonia.ResultsAnemia and interstitial pneumonia both significantly improved following treatment with a Janus kinase 2 gene inhibitor. In this report, we discuss the possible mechanisms underlying PMF complicated with ILD.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/53e1a58b4ef64a9c96377a13fc354b2a Zobrazit plný text záznamu View record in DOAJ