Autor: |
Rahul Negi, Manasa Kalivemula, Karan Bisht, Manjushree Bhate, Virender Sachdeva, Shrikant R. Bharadwaj |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Frontiers in Ophthalmology, Vol 4 (2024) |
Druh dokumentu: |
article |
ISSN: |
2674-0826 |
DOI: |
10.3389/fopht.2024.1396511 |
Popis: |
PurposeTo describe the construction and diagnostic accuracy of a modularized, virtual reality (VR)-based, pupillometer for detecting relative afferent pupillary defect (RAPD) in unilateral optic neuropathies, vis-à-vis, clinical grading by experienced neuro-ophthalmologists.MethodsProtocols for the swinging flashlight test and pupillary light response analysis used in a previous stand-alone pupillometer was integrated into the hardware of a Pico Neo 2 Eye® VR headset with built-in eye tracker. Each eye of 77 cases (mean ± 1SD age: 39.1 ± 14.9yrs) and 77 age-similar controls were stimulated independently thrice for 1sec at 125lux light intensity, followed by 3sec of darkness. RAPD was quantified as the ratio of the direct reflex of the stronger to the weaker eye. Device performance was evaluated using standard ROC analysis.ResultsThe median (25th – 75th quartiles) pupil constriction of the affected eye of cases was 38% (17 – 23%) smaller than their fellow eye (p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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