Diagnostic utility of 3D DIR MRI in the estimation of MS lesions overall load with special emphasis on cortical subtypes

Autor: Ahmed S. Abdelrahman, Nivan Hany Khater, Mai M. K. Barakat
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: The Egyptian Journal of Radiology and Nuclear Medicine, Vol 53, Iss 1, Pp 1-9 (2022)
Druh dokumentu: article
ISSN: 2090-4762
DOI: 10.1186/s43055-022-00719-x
Popis: Abstract Background A number of magnetic resonance imaging studies have shown that a significant proportion of multiple sclerosis (MS) lesions are located in the cerebral cortex and correlate with the patient's disability level. Double inversion recovery (DIR) has a higher sensitivity to detect cortical lesions and their different types. The aim of our study was to assess the superiority of 3D DIR as compared to FLAIR in detecting the different cortical subtypes and to enhance its role as a test for the clinical disability of the patient. Results The current study included 82 MS patients (60 female and 22 male with mean age of 34.5 ± 8.2 years); 59 cases having relapsing–remitting MS, 5 having secondary progressive MS, and 4 having primary progressive MS, as well as eight clinically isolated syndrome cases, and six radiologically isolated syndrome cases. DIR was superior to FLAIR in MS plaque number detection of cortical plaque-types 1, 2, 3 and 4 with a p value
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