Analysis of 5-hydroxytryptamine and its related indoles in cerebrospinal fluid of leukemic children by gas chromatography-mass spectrometry
| Autor: | Zhang Pingping, Wang Bo, Sun Yanmei, Gao Jian, Lian Kaoqi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Journal of Laboratory Medicine, Vol 44, Iss 1, Pp 41-45 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2567-9430 2567-9449 |
| DOI: | 10.1515/labmed-2019-0156 |
| Popis: | It is meaningful to quantify some neurotransmitters in cerebrospinal fluid (CSF) for pathology and clinical diagnosis. The objective of this study was to develop a rapid and reliable method for detecting 5-hydroxyindole ethanol (5-HTOL), 5-hydroxyindole acetic acid (5-HIAA), 5-hydroxytryptophan (5-HTP) and 5-hydroxytryptamine (5-HT) in CSF by gas chromatography-mass spectrometry (GC-MS), and explore the clinical significance of the levels of these neurotransmitters in CSF from acute lymphoblastic leukemia (ALL). |
| Databáze: | Directory of Open Access Journals |
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