Chemistry of Substituted Quinolinones. Part VI. Synthesis and Nucleophilic Reactions of 4-Chloro-8-methylquinolin-2(1H)-one and its Thione Analogue

Autor:	Mohamed M. Hassan, Mohamed Abass, Mostafa M. Ismail
Jazyk:	angličtina
Rok vydání:	2000
Předmět:	quinolinone quinolinethione nucleophilic substitution thiol-thione tautomerism mass fragmentation Organic chemistry QD241-441
Zdroj:	Molecules, Vol 5, Iss 12, Pp 1224-1239 (2000)
Druh dokumentu:	article
ISSN:	51201224 1420-3049
DOI:	10.3390/51201224
Popis:	The synthesis of 4-chloro-8-methylquinolin-2(1H)-one and its thione analogue is described. Some nucleophilic substitution reactions of the 4-chloro group were carried out to get new 4-substituted 2-quinolinones and quinolinethiones, such as 4-sulfanyl, hydrazino, azido and amino derivatives, which are of important synthetic use. The structure of the new compounds was established by their elemental analysis, IR and 1H-NMR spectra. Also the mass fragmentation pattern of some products is discussed.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/53ae6b8bdf1d4db29e2ad67a56b3e0e2 Zobrazit plný text záznamu View record in DOAJ