| Autor: |
S. Pascual, B. Noble, N. Ahmad-Saeed, C. Aldridge, S. Ambretti, S. Amit, R. Annett, S. A. O'Shea, A. M. Barbui, G. Barlow, L. Barrett, M. Berth, A. Bondi, N. Boran, S. E. Boyd, C. Chaves, M. Clauss, P. Davies, I. T. Dianzo-Delgado, J. Esteban, S. Fuchs, L. Friis-Hansen, D. Goldenberger, A. Kraševac Glaser, J. O. Groonroos, I. Hoffmann, T. Hoffmann, H. Hughes, M. Ivanova, P. Jezek, G. Jones, Z. Ceren Karahan, C. Lass-Flörl, F. Laurent, L. Leach, M. L. Horsbøll Pedersen, C. Loiez, M. Lynch, R. J. Maloney, M. Marsh, O. Milburn, S. Mitchell, L. S. P. Moore, L. Moffat, M. Murdjeva, M. E. Murphy, D. Nayar, G. Nigrisoli, F. O'Sullivan, B. Öz, T. Peach, C. Petridou, M. Prinz, M. Rak, N. Reidy, G. M. Rossolini, A.-L. Roux, P. Ruiz-Garbajosa, K. Saeed, L. Salar-Vidal, C. Salas Venero, M. Selvaratnam, E. Senneville, P. Starzengruber, B. Talbot, V. Taylor, R. Trebše, D. Wearmouth, B. Willinger, M. Wouthuyzen-Bakker, B. Couturier, F. Allantaz |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Journal of Bone and Joint Infection, Vol 9, Pp 87-97 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2206-3552 |
| DOI: |
10.5194/jbji-9-87-2024 |
| Popis: |
Introduction: The BIOFIRE Joint Infection (JI) Panel is a diagnostic tool that uses multiplex-PCR testing to detect microorganisms in synovial fluid specimens from patients suspected of having septic arthritis (SA) on native joints or prosthetic joint infections (PJIs). Methods: A study was conducted across 34 clinical sites in 19 European and Middle Eastern countries from March 2021 to June 2022 to assess the effectiveness of the BIOFIRE JI Panel. Results: A total of 1527 samples were collected from patients suspected of SA or PJI, with an overall agreement of 88.4 % and 85 % respectively between the JI Panel and synovial fluid cultures (SFCs). The JI Panel detected more positive samples and microorganisms than SFC, with a notable difference on Staphylococcus aureus, Streptococcus species, Enterococcus faecalis, Kingella kingae, Neisseria gonorrhoeae, and anaerobic bacteria. The study found that the BIOFIRE JI Panel has a high utility in the real-world clinical setting for suspected SA and PJI, providing diagnostic results in approximately 1 h. The user experience was positive, implying a potential benefit of rapidity of results' turnover in optimising patient management strategies. Conclusion: The study suggests that the BIOFIRE JI Panel could potentially optimise patient management and antimicrobial therapy, thus highlighting its importance in the clinical setting. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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