Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males

Autor: Debashish U. Menon, Oleksandr Kirsanov, Christopher B. Geyer, Terry Magnuson
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-26828-1
Popis: The mammalian SWI/SNF nucleosome remodeler is required for spermatogenesis. Here, the authors show that PBAF is essential for meiotic cell division in males and required to activate the expression of critical genes involved in spindle assembly and nuclear division in spermatocytes.
Databáze: Directory of Open Access Journals