| Autor: |
Pao-Yu Chen, Jann-Tay Wang, Sui-Yuan Chang, Chien-Ching Hung, Chi-Tai Fang, Aristine Cheng, Wang-Da Liu, Yu-Shan Huang, Kuan-Yin Lin, Hsin-Yun Sun, Sung-Ching Pan, Yu-Cheng Cheng, Hurng-Yi Wang, Wang-Huei Sheng, Yee-Chun Chen, Yi-Lwun Ho, Ming-Shiang Wu, Shan-Chwen Chang |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Journal of the Formosan Medical Association, Vol 122, Iss 8, Pp 766-775 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
0929-6646 |
| DOI: |
10.1016/j.jfma.2023.02.008 |
| Popis: |
Background: COVID-19 rebound is usually reported among patients experiencing concurrent symptomatic and viral rebound. But longitudinal viral RT-PCR results from early stage to rebound of COVID-19 was less characterized. Further, identifying the factors associated with viral rebound after nirmatrelvir-ritonavir (NMV/r) and molnupiravir may expand understanding of COVID-19 rebound. Methods: We retrospectively analyzed clinical data and sequential viral RT-PCR results from COVID-19 patients receiving oral antivirals between April and May, 2022. Viral rebound was defined by the degree of viral load increase (ΔCt ≥ 5 units). Results: A total of 58 and 27 COVID-19 patients taking NMV/r and molnupiravir, respectively, were enrolled. Patients receiving NMV/r were younger, had fewer risk factors for disease progression and faster viral clearance rate compared to those receiving molnupiravr (All P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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