Genetic Factors and the Risk of Periodontitis Development: Findings from a Systematic Review Composed of 13 Studies of Meta-Analysis with 71,531 Participants

Autor: Maélson Klever da Silva, Antonio Carlos Gonçalves de Carvalho, Even Herlany Pereira Alves, Felipe Rodolfo Pereira da Silva, Larissa dos Santos Pessoa, Daniel Fernando Pereira Vasconcelos
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: International Journal of Dentistry, Vol 2017 (2017)
Druh dokumentu: article
ISSN: 1687-8728
1687-8736
DOI: 10.1155/2017/1914073
Popis: Purpose. This work aimed to synthesize the results of recent meta-analysis focusing on polymorphism in inflammatory mediators and its relation with the risk of periodontitis development. Materials and Methods. A systematic search was conducted using databases for publications prior to October 2016. Three examiners extracted data from articles with a clear association between polymorphisms in the inflammatory mediator gene and the development of periodontitis through meta-analysis using the fixed or randomized statistical models to calculate the Odds Ratio with values of P
Databáze: Directory of Open Access Journals