Acute localized exanthematous pustulosis: A novel side effect of piroxicam

Autor: Soukaina Maghfour, Monia Youssef, Rim Hadhri, Ines Lahouel, Yosra Soua, Mouna Korbi, Hichem Belhadjali, Jameleddine Zili
Jazyk: English<br />Spanish; Castilian<br />French<br />Polish
Rok vydání: 2022
Předmět:
Zdroj: Nasza Dermatologia Online, Vol 13, Iss 1, Pp 65-66 (2022)
Druh dokumentu: article
ISSN: 2081-9390
DOI: 10.7241/ourd.20221.15
Popis: Acute generalized exanthematous pustulosis (AGEP) is a rare yet well-known cutaneous reaction pattern, mostly caused by drugs. Acute localized exanthematous pustulosis (ALEP) is a localized variant of AGEP. A 42-year-old female presented with multiple erythematous pustules on the face, which appeared three days after the intramuscular injection of piroxicam. Histopathology revealed subcorneal pustules, epidermal spongiosis, and mixed inflammatory cell infiltration in the dermis. The pustules resolved within several days once the patient had discontinued the drug. Herein, we report the first case, as far as we know, of a female with a cutaneous drug reaction consistent with ALEP caused by piroxicam.
Databáze: Directory of Open Access Journals