Spectroscopic correlation and role of Azathioprine in long-term remission in patients of Hashimoto encephalopathy
| Autor: | Harpreet Singh, Sucharita Ray, Shalini Agarwal, Raj Pal Verma, Paulomi Talapatra, Vikas Gupta |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Annals of Indian Academy of Neurology, Vol 16, Iss 3, Pp 443-446 (2013) |
| Druh dokumentu: | article |
| ISSN: | 0972-2327 1998-3549 |
| DOI: | 10.4103/0972-2327.116936 |
| Popis: | Hashimoto encephalopathy remains a Rubik′s cube for the present generation of clinical research. Myriad presentations have been noted, and observations recorded in few subgroups of patients have gone on only to be trashed by a second group of patients with a completely different clinical profile. Steroids have been traditionally held to be the treatment for this condition, but long-term side effects associated with it limits its use. Although multiple drugs have been tried, yet there exists no data for their long-term efficacy in maintaining remission. No radiological findings have been consistently associated with this condition. We report the use of azathioprine in maintaining long-term remission in one such patient with Hashimoto encephalopathy and the presence of lactate peak in magnetic resonance spectroscopy of the patient, which showed dramatic regression with institution of immunosuppression. |
| Databáze: | Directory of Open Access Journals |
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