Dermatomyositis Associated With High-Grade B-Lymphoproliferative Disorders: A Case Report and Literature Review

Autor: Jun Yen Ng MBBS, Mridula Mokoonlall FRACP, FRCPA, Hana Kawatu MD, Fathima Ayyalil FRACP, FRCPA, Chandima Perera FRACP, Adrienne Morey FRCPA, Nalini K. Pati FRACP, FRCPA
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Investigative Medicine High Impact Case Reports, Vol 12 (2024)
Druh dokumentu: article
ISSN: 2324-7096
23247096
DOI: 10.1177/23247096241262702
Popis: Dermatomyositis (DM) and polymyositis are idiopathic inflammatory myopathies (IIMs), most associated with solid organ malignancies, and less commonly hematological malignancies. We discuss a case of DM associated with diffuse large B-cell lymphoma, followed by a review of literature on the pathogenesis, clinical course, treatment, and prognosis. Various challenges with the diagnosis and management of underlying lymphoproliferative disorders (LPDs) in patients with IIM are discussed. The case demonstrates the importance of being vigilant of the association between IIM and LPD. Cancer screening in patients with IIM is discussed, including the recently published International Guideline for IIM-Associated Cancer Screening. More research is required to address knowledge gaps in cancer screening in IIM.
Databáze: Directory of Open Access Journals