Incidence of Long‐Term Structural Valve Dysfunction and Bioprosthetic Valve Failure After Transcatheter Aortic Valve Replacement

Autor: Marco Barbanti, Giuliano Costa, Paolo Zappulla, Denise Todaro, Andrea Picci, Giulia Rapisarda, Emanuela Di Simone, Rita Sicuso, Sergio Buccheri, Simona Gulino, Gerlando Pilato, Ketty La Spina, Paolo D'Arrigo, Roberto Valvo, Antonino Indelicato, Daniela Giannazzo, Sebastiano Immè, Claudia Tamburino, Martina Patanè, Carmelo Sgroi, Angelo Giuffrida, Danilo Trovato, Ines Paola Monte, Wanda Deste, Piera Capranzano, Davide Capodanno, Corrado Tamburino
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 15 (2018)
Druh dokumentu: article
ISSN: 2047-9980
DOI: 10.1161/JAHA.117.008440
Popis: Background Long‐term data on durability of currently available transcatheter heart valves are sparse. We sought to assess the incidence of long‐term (8‐year) structural valve dysfunction and bioprosthetic valve failure in a cohort of patients with transcatheter aortic valve replacement (TAVR) who reached at least 5‐year follow‐up. Methods and Results Consecutive patients with at least 5‐year follow‐up available undergoing TAVR from June 4, 2007 to March 30, 2012 were included. Structural valve dysfunction and bioprosthetic valve failure were defined according to newly standardized European Association of Percutaneous Cardiovascular Interventions/European Society of Cardiology/European Association for Cardio‐Thoracic Surgery criteria and reported as cumulative incidence function to account for the competing risk of death. A total of 288 consecutive patients with a mean age of 80.7±5.3 years and with a mean Society of Thoracic Surgery mortality score of 8.1±5.1% were analyzed. Survival rate at 8 years was 29.8%. Mean pressure gradients decreased from 53.3±15.9 mm Hg (pre‐TAVR) to 10.5±4.5 mm Hg (in‐hospital post‐TAVR) (P
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