Association of insertion deletion polymorphism of the ACE gene with factors of circulating rennin-angiotensin-aldosterone system and endothelial function of skin microvassals in preeclampsia
| Autor: | O. V. Radkov, M. N. Kalinkin, V. V. Zavarin |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Бюллетень сибирской медицины, Vol 10, Iss 4, Pp 32-36 (2011) |
| Druh dokumentu: | article |
| ISSN: | 1682-0363 1819-3684 87385937 |
| DOI: | 10.20538/1682-0363-2011-4-32-36 |
| Popis: | The association of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) gene polymorphism with plasma ACE, renin activity and endothelial function of skin microvassals were studied. Preeclamptic patients with the DD genotype of ACE I/D gene polymorphism have lowest plasma renin activity level and endothelium-dependent vasodilatation, D allele carriers have highest plasma ACE activity. |
| Databáze: | Directory of Open Access Journals |
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