Autor: |
Wael Hafez, Mohamad Azzam Ziade, Arun Arya, Husam Saleh, Sara Ali, Srinivasa Raghu Rao, Osman Fdl Alla, Mohamed Ali, Mouhamad Al Zouhbi, Ahmed Abdelrahman |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
International Journal of Infectious Diseases, Vol 117, Iss , Pp 334-344 (2022) |
Druh dokumentu: |
article |
ISSN: |
1201-9712 |
DOI: |
10.1016/j.ijid.2022.02.019 |
Popis: |
Background: Low ADAMTS13 activity has been suggested to be an interplaying factor in the pathogenesis of COVID-19, considering that it is a thromboinflammatory disease with high risk of microthrombosis. Objectives: The study aimed to explore the correlation between ADAMTS13 activity and the pathophysiological pathway of COVID-19. Methods: We carried out a retrospective observational study of 87 patients with COVID-19 in NMC Royal Hospital, Abu Dhabi, UAE. ADAMTS13 activity was measured and compared with patients’ characteristics and clinical outcomes. Results: Low ADAMTS13 activity was associated with pneumonia (p = 0.007), severity of COVID-19 (p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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