Simultaneous integrated boost by Intensity Modulated Radiotherapy (SIB-IMRT) in patients undergoing breast conserving surgery – A clinical and dosimetric perspective

Autor: Abhinav Dewan, Kundan Singh Chufal, Ajay Kumar Dewan, Anjali Pahuja, Krati Mehrotra, Rajpal Singh, Rahul Lal Chaudhary, T. Suresh, Maninder Mishra, Abirama V. Sundari, Sravya Bommera, Raman Narang, Preeti Pathak, Swarupa Mitra, SK Sharma, Munish Gairola
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Journal of the Egyptian National Cancer Institute, Vol 30, Iss 4, Pp 165-171 (2018)
Druh dokumentu: article
ISSN: 1110-0362
DOI: 10.1016/j.jnci.2018.10.001
Popis: Aim: To study feasibility of simultaneous integrated boost by intensity modulated radiotherapy (SIB-IMRT) in patients undergoing breast conserving surgery and its impact on cosmesis and dosimetry. Patients and methods: Between January 2014 and June 2017, all breast cancer patients fulfilling inclusion and exclusion criteria were enrolled in a prospective study conducted at a tertiary cancer centre in North India. All patients received adjuvant radiotherapy by simultaneous integrated boost technique following breast conserving surgery. Clinical information including patient and pathological characteristics, observed acute and chronic toxicities along with cosmesis using Harvard score were recorded and analysed. Univariate analysis and multivariate logistic regression analysis were performed for those variables which were found to be significant (p
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