Thrombo-inflammatory prognostic score can predict the outcome of stroke: a retrospective cohort study

Autor: Xingyu Zhu, Lin Lan, Yi Liu, Na He, Jie Wu, Yingqiang Guo, Hong Li, Dongze Li
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Aging Neuroscience, Vol 16 (2024)
Druh dokumentu: article
ISSN: 1663-4365
DOI: 10.3389/fnagi.2024.1391559
Popis: IntroductionInflammatory and thrombotic biomarkers are simple prognostic indicators of adverse clinical outcomes in patients with ischemic stroke (IS). However, isolated assessment of inflammatory or thrombus biomarkers in patients with IS is limited in clinical practice.MethodsThis study aimed to evaluate the predictive value of a novel, simplified thrombo-inflammatory prognostic score (TIPS) that combines both inflammatory and thrombus biomarkers in the early phase of IS and to identify high-risk patients at the time of admission. The study population comprised 915 patients with a primary diagnosis of IS in the emergency departments of five grade A tertiary hospitals in China.ResultsPatients were divided into two groups based on the modified Rankin Scale (mRS):
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