Honing-in antigen-specific cells during antibody discovery: a user-friendly process to mine a deeper repertoire

Autor: Ankit Mahendra, Aftabul Haque, Ponraj Prabakaran, Brian C. Mackness, Thomas P. Fuller, Xiaohua Liu, Sagar V. Kathuria, Yui-Hsi Wang, Nilesh Amatya, Xiaocong Yu, Joern Hopke, Dietmar Hoffmann, Eva Bric-Furlong, Ningning Zhang, Hyun-Suk Cho, Ruijun Zhang, Jose Sancho, Jacqueline Saleh, Sambasiva P. Rao, Maria Wendt, Partha S. Chowdhury
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-022-04129-7
Popis: The authors developed a methodology for bulk enrichment of antigen-specific B cells to improve the diversity of antibody sequences and increase the number of functional antigen-specific antibodies coming from different antibody generation platforms.
Databáze: Directory of Open Access Journals
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