Autor: |
Joycelyn Smith, Rajendra Neupane, William McAmis, Udai Singh, Saurabh Chatterjee, Samir Raychoudhury |
Jazyk: |
angličtina |
Rok vydání: |
2019 |
Předmět: |
|
Zdroj: |
Toxicology Reports, Vol 6, Iss , Pp 1176-1181 (2019) |
Druh dokumentu: |
article |
ISSN: |
2214-7500 |
DOI: |
10.1016/j.toxrep.2019.11.006 |
Popis: |
Polycyclic Aromatic Hydrocarbons (PAHs) are environmental pollutants.The present study compares the toxic effects of BaP alone and a mixture of PAHs on human breast cancer cells. We hypothesize that PAH mixture is more toxic than BaP alone, and an increased NOX2 activation is related to PAH-induced oxidative stress. Initially, we exposed cultured human breast cancer cells to BaP alone (125 ng/mL and 500 ng/mL) and a mixture of PAHs (125 ng/mL and 500 ng/mL). After 24 h of exposure, the PAH mixture demonstrated a significant (P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
|