| Autor: |
Joycelyn Smith, Rajendra Neupane, William McAmis, Udai Singh, Saurabh Chatterjee, Samir Raychoudhury |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Toxicology Reports, Vol 6, Iss , Pp 1176-1181 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2214-7500 |
| DOI: |
10.1016/j.toxrep.2019.11.006 |
| Popis: |
Polycyclic Aromatic Hydrocarbons (PAHs) are environmental pollutants.The present study compares the toxic effects of BaP alone and a mixture of PAHs on human breast cancer cells. We hypothesize that PAH mixture is more toxic than BaP alone, and an increased NOX2 activation is related to PAH-induced oxidative stress. Initially, we exposed cultured human breast cancer cells to BaP alone (125 ng/mL and 500 ng/mL) and a mixture of PAHs (125 ng/mL and 500 ng/mL). After 24 h of exposure, the PAH mixture demonstrated a significant (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
