Effect of red maca (Lepidium meyenii) on INF-γ levels in ovariectomized rats
| Autor: | Johanna Leiva-Revilla, Félix Guerra-Castañon, Paola Olcese-Mori, Iván Lozada, Julio Rubio, Carla Gonzales, Gustavo F Gonzales |
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| Jazyk: | Spanish; Castilian |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Revista Peruana de Medicina Experimental y Salud Pública, Vol 31, Iss 4 (2014) |
| Druh dokumentu: | article |
| ISSN: | 1726-4634 1726-4642 |
| DOI: | 10.17843/rpmesp.2014.314.118 |
| Popis: | Objectives. Compare the effect of different doses of red maca on gamma interferon (IFN-γ) levels in ovariectomized rats (OVX). Materials and methods. Adult female rats were randomly divided into the following six groups: Group 1: pseudo-ovariectomized rats (PO); Group 2: OVX rats; Group 3: OVX rats treated with 4 ug/kg estradiol; and Group 4, 5 and 6: OVX rats treated with red maca extracts with 2.15, 4.3 and 8.6 mg polyphenols/body weight kilogram, respectively. Results. OVX rats showed low levels of IFN-γ compared to PO rats. Estradiol and red maca reversed the effect of ovariectomy on the IFN-γ levels. A positive dose-response effect of red maca on IFN-γ levels was shown (r = 0.57, p 0.05). Conclusions. Red maca administration increases levels of IFN-γ in ovariectomized rats. |
| Databáze: | Directory of Open Access Journals |
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