| Autor: |
Jacob M. Maskal, Luiz F. Brito, Alan W. Duttlinger, Kouassi R. Kpodo, Betty R. McConn, Christopher J. Byrd, Brian T. Richert, Jeremy N. Marchant, Donald C. Lay, Shelbi D. Perry, Matthew C. Lucy, Tim J. Safranski, Jay S. Johnson |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-021-01889-w |
| Popis: |
Abstract In utero heat stress alters postnatal physiological and behavioral stress responses in pigs. However, the mechanisms underlying these alterations have not been determined. The study objective was to characterize the postnatal hypothalamic–pituitary–adrenal axis response of in utero heat-stressed pigs. Pigs were subjected to a dexamethasone suppression test followed by a corticotrophin releasing hormone challenge at 10 and 15 weeks of age. Following the challenge, hypothalamic, pituitary, and adrenal tissues were collected from all pigs for mRNA abundance analyses. At 10 weeks of age, in utero heat-stressed pigs had a reduced (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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