Regionalized tissue fluidization is required for epithelial gap closure during insect gastrulation

Autor: Akanksha Jain, Vladimir Ulman, Arghyadip Mukherjee, Mangal Prakash, Marina B. Cuenca, Lokesh G. Pimpale, Stefan Münster, Robert Haase, Kristen A. Panfilio, Florian Jug, Stephan W. Grill, Pavel Tomancak, Anastasios Pavlopoulos
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-19356-x
Popis: The mechanics of embryonic tissue spreading over spherical eggs is not fully understood. Here, the authors show that during gastrulation in the red flour beetle, extraembryonic tissue epiboly is facilitated by local actomyosin-mediated fluidization of the tissue at the leading edge.
Databáze: Directory of Open Access Journals