Autor: |
Melike Sezgin Evim, Özlem Tüfekçi, Birol Baytan, Hale Ören, Solmaz Celebi, Beyza Ener, Kevser Üstün Elmas, Şebnem Yılmaz, Melek Erdem, Mustafa Kemal Hacımustafaoğlu, Adalet Meral Güneş |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
|
Zdroj: |
Turkish Journal of Hematology, Vol 39, Iss 2, Pp 94-102 (2022) |
Druh dokumentu: |
article |
ISSN: |
1308-5263 |
DOI: |
10.4274/tjh.galenos.2021.2021.0203 |
Popis: |
Objective: The incidence of invasive fungal infections (IFIs) has increased due to intensive chemotherapy in childhood leukemia. The aim of this study was to evaluate the incidence, risk factors, causative pathogens, and impact on survival of IFIs among pediatric leukemia patients. Materials and Methods: The hospital records of 307 children with acute lymphoblastic leukemia (ALL, n=238), acute myeloid leukemia (AML, n=51), and relapsed leukemia (n=18) between January 2010 and December 2015 were retrospectively evaluated. Results: A total of 1213 febrile neutropenia episodes were recorded and 127 (10.4%) of them were related to an IFI. Of 307 children, 121 (39.4%) developed IFIs. The mean age was significantly older in the IFI group compared to children without IFIs (p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
|