Autoimmunity and Immunotherapy in Narcolepsy

Autor:	Min Jae Seong, Seung Bong Hong
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	Narcolepsy Autoimmune Immunoglobulin. Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Zdroj:	Sleep Medicine Research, Vol 8, Iss 1, Pp 1-7 (2017)
Druh dokumentu:	article
ISSN:	2093-9175 2233-8853
DOI:	10.17241/smr.2017.00052
Popis:	Narcolepsy is a neurological disorder characterized by excessive daytime sleepiness, cataplexy, hypnagogic hallucination, and sleep paralysis. Narcolepsy is caused by damage of hypocretin producing neurons in the lateral hypothalamus. The association of narcolepsy with HLA DQB1*0602 and high incidence following H1N1 pandemic in china, vaccination with pandemrix and an adjuvanted H1N1 vaccine suggests that pathophysiology of narcolepsy is involved in the immune system. This review focused on immunological associations and immunotherapy in narcolepsy.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/527d88b0553d4de189fa987047ea843c Zobrazit plný text záznamu View record in DOAJ