Autor: |
Thergiory Irrazabal, Bhupesh K. Thakur, Mingsong Kang, Yann Malaise, Catherine Streutker, Erin O. Y. Wong, Julia Copeland, Robert Gryfe, David S. Guttman, William W. Navarre, Alberto Martin |
Jazyk: |
angličtina |
Rok vydání: |
2020 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-020-15549-6 |
Popis: |
It is unclear how microbial-induced inflammation promotes neoplastic transformation in colitis-associated cancer (CAC). Here, the authors use models of CAC to show that inflammation induces 8-oxoguanine lesions in DNA, and that antioxidants can reduce these DNA lesions as well as CAC. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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