Effect of electromyostimulation on intramyocellular lipids of the vastus lateralis in older adults: a randomized controlled trial

Autor: Maya Hioki, Nana Kanehira, Teruhiko Koike, Akira Saito, Hideyuki Takahashi, Kiyoshi Shimaoka, Hisataka Sakakibara, Yoshiharu Oshida, Hiroshi Akima
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-11 (2021)
Druh dokumentu: article
ISSN: 1471-2474
DOI: 10.1186/s12891-021-04456-6
Popis: Abstract Background Excessive intramyocellular lipid (IMCL) accumulation is a primary cause of skeletal muscle insulin resistance, especially in older adults, and interventions that reduce IMCL contents are important to improve insulin sensitivity. Electromyostimulation (EMS)-induced changes in IMCL content in older adults remain unknown. The purpose of this study was to clarify the effects of a single bout of EMS on the IMCL content of the vastus lateralis muscle in older adults. Methods Twenty-two physically active, non-obese older men and women were randomly assigned to an EMS intervention group (69.0 ± 5.2 years, n = 12) or a control group (68.4 ± 3.5 years, n = 10). EMS was applied to the vastus lateralis (7 s on and 7 s off) for 30 min; control participants sat quietly for 30 min. IMCL content within the vastus lateralis was quantified with 1H-magnetic resonance spectroscopy (n = 7 per group). Fasting plasma glucose and insulin values were determined from blood samples collected before and after the EMS intervention. Results EMS induced a significant reduction in plasma glucose (93.1 ± 9.6 to 89.5 ± 9.1 mg/dL, p
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