Faster rehabilitation weight gain is associated with liver fat in adult survivors of childhood severe acute malnutrition

Autor: Debbie Thompson, Kimberley McKenzie, Asha Badaloo, Carolyn Taylor-Bryan, Ingrid Tennant, Deanne Soares, Terrence Forrester, Michael Boyne
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: World Nutrition, Vol 13, Iss 4 (2022)
Druh dokumentu: article
ISSN: 2041-9775
DOI: 10.26596/wn.20221345-14
Popis: Background Nutritional rehabilitation during severe acute malnutrition (SAM) aims to quickly restore a healthy body weight, but rapid weight gain has been associated with later cardiovascular risk. We hypothesized that faster weight gain during SAM rehabilitation and post-hospitalization is associated with liver fat in adult survivors. Method Jamaican adult survivors of childhood SAM underwent abdominal CT scan to estimate liver fat as mean liver attenuation (MLA) and liver spleen ratio (L/S). Birth weight (BW) and anthropometry measured during, and post-hospitalization were abstracted from admission records. Results We studied 42 marasmus survivors (MRs) and 40 kwashiorkor survivors (KWs). MRs had a lower mean BW (SD) 2.5 (0.8) vs 3.0 (0.7) kg; p=0.01) and were more wasted (p
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