| Autor: |
Rutger C. C. Hengeveld, Martijn J. M. Vromans, Mathijs Vleugel, Michael A. Hadders, Susanne M. A. Lens |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/ncomms15542 |
| Popis: |
Precise chromosome segregation during mitosis requires coordination of stable chromosome bi-orientation with anaphase onset, however the underlying mechanism is not clear. Here the authors show that inner centromere localization of the chromosomal passenger complex maintains centromeric cohesion on bi-oriented chromosomes and allows mitotic checkpoint silencing. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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