Study of T-cell subsets, B and NK cells in Iranian patients with Behcet's disease by monoclonal antibodies
| Autor: | Rayyani M, Masoud A, Davachi F |
|---|---|
| Jazyk: | perština |
| Rok vydání: | 1995 |
| Předmět: | |
| Zdroj: | Tehran University Medical Journal, Vol 53, Iss 1, Pp 19-23 (1995) |
| Druh dokumentu: | article |
| ISSN: | 1683-1764 1735-7322 |
| Popis: | Behcet disease (BD) is a systemic inflammatory disease of the unknown etiology. There is however, some evidence to suggest that immunological abnormalities are important in its pathogenesis, furthermore several T-cell abnormalities which may be quite relevant to autoimmune origin of the disease have been described. We report here our study of T-cell subsets, B and NK cells in 68 patients with BD in comparison to 30 normal controls, by monoclonal antibodies against CD3 (pan T-cell), CD4 (Helper) CD8 (Suppressor/cytotoxic), CD22 (B-cell) and CD16 (NK-cell) markers. The results show the increase (P=0.008) of T (CD3), T (CD4) (P |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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