Hypolipidemic effects and mechanisms of Val-Phe-Val-Arg-Asn in C57BL/6J mice and 3T3-L1 cell models

Autor: Xing Zhang, Wen Shi, Hui He, Ruge Cao, Tao Hou
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Functional Foods, Vol 73, Iss , Pp 104100- (2020)
Druh dokumentu: article
ISSN: 1756-4646
DOI: 10.1016/j.jff.2020.104100
Popis: Val-Phe-Val-Arg-Asn (VFVRN) has been identified and screened from lipid-lowering chickpea peptides (ChPs) previously. This work explored its lipid-lowering mechanisms by using a high-fat diet C57BL/6J mice model and 3T3-L1 preadipocyte cell model. Administration of VFVRN to hyperlipidemic mice significantly decreased the levels of total cholesterol (TC) and total triglyceride (TG) in liver and serum (P
Databáze: Directory of Open Access Journals