Evulation of Antimutagenic Activity of Ni(II) Complexes with Unsymmetric Schiff Bases

Autor: Elvan Hasanoğlu Özkan, Dilek Nartop, Güleray Ağar, Hamit Emre Kızıl, Nurşen Sarı
Jazyk: English<br />Turkish
Rok vydání: 2020
Předmět:
Zdroj: Düzce Üniversitesi Bilim ve Teknoloji Dergisi, Vol 8, Iss 1, Pp 608-616 (2020)
Druh dokumentu: article
ISSN: 2148-2446
DOI: 10.29130/dubited.575747
Popis: In this work, Ni(II) complexes with unsymmetric Schiff bases (NiL1, NiL2, NiL3, NiL4) were prepared by a two-stage method reported by one of us recently for investigate antimutagenic properties. Sodium azide-induced antimutagenic effect in lymphocytes was determined by sister chromatid exchange (SCE) and micronucleus (MN) methods. It has been determined that the synthesized compounds have antimutagenic properties and reduce the mutagenicity caused by sodium azide (NaN3) which is used as a positive control.
Databáze: Directory of Open Access Journals