| Autor: |
Sevda Hassan, Lisa Mumford, Susan Robinson, Dora Foukanelli, Nick Torpey, Rutger J. Ploeg, Nizam Mamode, Michael F. Murphy, Colin Brown, David J. Roberts, Fiona Regan, Michelle Willicombe |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Frontiers in Nephrology, Vol 3 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2813-0626 |
| DOI: |
10.3389/fneph.2023.1236520 |
| Popis: |
BackgroundPatient Blood Management (PBM), endorsed by the World Health Organisation is an evidence-based, multi-disciplinary approach to minimise inappropriate blood product transfusions. Kidney transplantation presents a particular challenge to PBM, as comprehensive evidence of the risk of transfusion is lacking. The aim of this study is to investigate the prevalence of post-transplant blood transfusions across multiple centres, to analyse risk factors for transfusion and to compare transplant outcomes by transfusion status.MethodsThis analysis was co-ordinated via the UK Transplant Registry within NHS Blood and Transplant (NHSBT), and was performed across 4 centres. Patients who had received a kidney transplant over a 1-year period, had their transfusion status identified and linked to data held within the national registry.ResultsOf 720 patients, 221(30.7%) were transfused, with 214(29.7%) receiving a red blood cell (RBC) transfusion. The proportion of patients transfused at each centre ranged from 20% to 35%, with a median time to transfusion of 4 (IQR:0-12) days post-transplant. On multivariate analysis, age [OR: 1.02(1.01-1.03), p=0.001], gender [OR: 2.11(1.50-2.98), p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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