Peculiarities of chemo-resistant HIV/AIDS-associated tuberculosis in patients who died from co-infection

Autor: A. S. Shalmin, E. M. Raznatovskya, R. М. Yasinskiy
Jazyk: English<br />Russian<br />Ukrainian
Rok vydání: 2013
Předmět:
Zdroj: Patologìâ, Iss 1, Pp 63-67 (2013)
Druh dokumentu: article
ISSN: 2310-1237
2306-8027
DOI: 10.14739/2310-1237.2013.1.15363
Popis: Introduction. Today the problem of spread of two epidemics - TB and HIV/AIDS is too complicated in Ukraine. This problem is significantly complicated by the spread of the other world's problem - resistant TB. The growth of the HIV epidemic influences the situation of multidrug-resistant tuberculosis (MRTB), which is also associated with disorders of antituberculosis immunity. According to the literature, the high incidence of MRTB is directly correlated with the prevalence of HIV infection and AIDS. Tuberculosis is the direct cause of death of up to 30.0% of patients with HIV infection and in 90.0% cases of AIDS. That’s why studying the clinical course of HIV/AIDS-associated tuberculosis and analysis of causes of death of these patients are highly actual today. The aim of the study. To determine the clinical course and causes of death in patients with chemo-resistant HIV/AIDS-associated tuberculosis. Materials and methods. 14 patients cards who died from chemo-resistant HIV/AIDS-associated tuberculosis and who were supervised and treated at Zaporizhzhya TB dispensaries during the period of 2010-2012 are analyzed in this article. The results of research. Among patients with chemo-resistant HIV/AIDS-associated tuberculosis there were 12 men (85.7%) and 2 (14.3%) women. The average age was 41.9 ± 1.8 years. There were 100% of unemployed patients, 8 patients (57.1%) were former prisoners, 4 (28.5%) patients were shelterless persons, 4 patients (28,5%) suffered from drug addiction and alcoholism. Antisocial lifestyle was in 8 (57.1%) cases. HIV-infection started significantly (P
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