| Autor: |
Hamza Mehdaoui, Hamid Ait Abderrahmane, Clement de Loubens, Faïçal Nait Bouda, Sofiane Hamani |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Gels, Vol 7, Iss 4, p 215 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2310-2861 |
| DOI: |
10.3390/gels7040215 |
| Popis: |
This paper discusses the spreading of gel-based ophthalmic formulation on the cornea surface assumed to be flat. We show that gel-based formulations exhibit rheological behaviors that the Herschel–Bulkley model can describe. The continuity and momentum equations are solved numerically using the monofluid formulation and the volume-of-fluid (VOF) method. We investigated the influence of the rheological properties, namely the consistency, the yield stress, and the flow behavior index, on the spreading of a gel-based artificial tear over the cornea surface. We propose optimal values of these properties for efficient gel-based artificial tears. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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